Acetyl-CoA Carboxylase alpha Antikörper (AA 2223-2346)

Produktnummer ABIN5701229

Der Kaninchen Polyklonal anti-Acetyl-CoA Carboxylase alpha Antikörper wird verwendet zum Nachweis von Acetyl-CoA Carboxylase alpha in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA, IP und IF.

Kurzübersicht für Acetyl-CoA Carboxylase alpha Antikörper (AA 2223-2346) (ABIN5701229)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-Acetyl-CoA Carboxylase alpha Antikörper

Bindungsspezifität: AA 2223-2346

Verwendungszweck: ACACA antibody

Immunogen:

Immunogen sequence: 2223-2346aa

Immunogen: acetyl-Coenzyme A carboxylase alpha

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:200-1:2000,IHC:1:20-1:200,IF:1:20-1:200,IP:1:200-1:2000

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00077(ACACA antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Andere Bezeichnung: ACACA

Hintergrund:

Synonyms: Acetyl-CoA carboxylase 1 (ACC1)|Acetyl-Coenzyme A carboxylase alpha (ACC-alpha)|ACACA|ACAC|ACC1|ACCA

Background: ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

Molekulargewicht: 270kDa

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effekt