CISD2 Antikörper

Produktnummer ABIN5700515

Der Kaninchen Polyklonal Anti-CISD2-Antikörper wurde für WB, ELISA, IHC, IF und IP validiert. Er ist geeignet, CISD2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CISD2 Antikörper (ABIN5700515)

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CISD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-CISD2 Antikörper

Immunogen: CDGSH iron sulfur domain 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01718(CISD2 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu CISD2

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Andere Bezeichnung: CISD2

Hintergrund: Synonyms:CDGSH2, ERIS, ZCD2 Background:Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

Molekulargewicht: 13-15 kDa

Gen-ID: 493856

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response