CISD2 Antikörper

Produktnummer ABIN5700515

Der Kaninchen Polyklonal anti-CISD2 Antikörper wird verwendet zum Nachweis von CISD2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC, IF und IP.

Kurzübersicht für CISD2 Antikörper (ABIN5700515)

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CISD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-CISD2 Antikörper

Verwendungszweck: CISD2 antibody

Immunogen: CDGSH iron sulfur domain 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01718(CISD2 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CISD2

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Andere Bezeichnung: CISD2

Hintergrund:

Synonyms: CDGSH iron-sulfur domain-containing protein 2|Endoplasmic reticulum intermembrane small protein|MitoNEET-related 1 protein (Miner1)|Nutrient-deprivation autophagy factor-1 (NAF-1)|CISD2|CDGSH2|ERIS|ZCD2

Background: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

Molekulargewicht: 13-15 kDa

Gen-ID: 493856

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response