ASNA1 Antikörper

Produktnummer ABIN5700288

Dieser Anti-ASNA1-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von ASNA1 in WB, ELISA, IHC, IF, IP und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ASNA1 Antikörper (ABIN5700288)

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-ASNA1 Antikörper

Verwendungszweck: GET3 antibody

Immunogen: arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab00643(ASNA1 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu ASNA1

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Andere Bezeichnung: GET3

Hintergrund:

Synonyms: ATPase GET3|Arsenical pump-driving ATPase|Arsenite-stimulated ATPase|Guided entry of tail-anchored proteins factor 3, ATPase|Transmembrane domain recognition complex 40 kDa ATPase subunit|hARSA-I|hASNA-I|GET3|ARSA|ASNA1|TRC40

Background: This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.

Molekulargewicht: 37-41 kDa

Gen-ID: 439

UniProt: O43681

Pathways: Positive Regulation of Peptide Hormone Secretion