alpha Adaptin Antikörper

Produktnummer ABIN5698814

Der Kaninchen Polyklonal Anti-alpha Adaptin-Antikörper wurde für WB, IHC, ELISA, IP und IF validiert. Er ist geeignet, alpha Adaptin in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für alpha Adaptin Antikörper (ABIN5698814)

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Adaptin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-alpha Adaptin Antikörper

Immunogen: adaptor-related protein complex 2, alpha 1 subunit

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:500-1:5000,IP:1:500-1:5000,IHC:1:20-1:200,IF:1:10-1:100

Kommentare:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00323(AP2A1 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu alpha Adaptin

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Andere Bezeichnung: alpha Adaptin

Hintergrund: Synonyms:ADTAA, alpha Adaptin, Alpha adaptin A, Alpha1 adaptin, AP 2 complex subunit alpha 1, AP2 ALPHA, AP2A1, CLAPA1 Background:This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.

Molekulargewicht: 108kDa

UniProt: O95782

Pathways: Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation