UMPS Antikörper

Produktnummer ABIN5698683

Der Kaninchen Polyklonal anti-UMPS Antikörper (ABIN5698683) detektiert spezifisch UMPS in WB, IHC, ELISA und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für UMPS Antikörper (ABIN5698683)

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UMPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-UMPS Antikörper

Verwendungszweck: UMPS antibody

Immunogen: uridine monophosphate synthetase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:500-1:5000,IP:1:200-1:2000,IHC:1:20-1:200

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab09253(UMPS antibody) at dilution of 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Andere Bezeichnung: UMPS

Hintergrund:

Synonyms: Uridine 5'-monophosphate synthase (UMP synthase)|UMPS

Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 26kDa

Gen-ID: 7372

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process