Lamin B2 Antikörper

Produktnummer ABIN5698092

Dieses Anti-Lamin B2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Lamin B2 in WB, IHC, ELISA, IF, FACS und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Lamin B2 Antikörper (ABIN5698092)

Target: Lamin B2 (LMNB2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)

Produktdetails anti-Lamin B2 Antikörper

Immunogen: lamin B2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04807(LMNB2 antibody) at dilution of 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu Lamin B2

Target: Lamin B2 (LMNB2)

Andere Bezeichnung: LMNB2

Hintergrund: Synonyms:LMN2 Background:This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Molekulargewicht: 66-68 kDa

Gen-ID: 84823

UniProt: Q03252

Pathways: Apoptose, Caspase Kaskade in der Apoptose