HORMAD1 Antikörper

Produktnummer ABIN5697876

Dieses Anti-HORMAD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HORMAD1 in ELISA, WB und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für HORMAD1 Antikörper (ABIN5697876)

Target: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HORMAD1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-HORMAD1 Antikörper

Immunogen: HORMA domain containing 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu HORMAD1

Target: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Andere Bezeichnung: HORMAD1

Hintergrund: Synonyms:NOHMA Background:Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks(DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin(MSUC) and meiotic prophase quality control in both sexes(By similarity).

Molekulargewicht: 45 kDa

Gen-ID: 84072

UniProt: Q86X24

Pathways: M Phase