Interleukin enhancer-binding factor 3 (ILF3) Antikörper

Produktnummer ABIN5696831

Der Kaninchen Polyklonal Anti--Antikörper wurde für WB, IHC, ELISA, IP und IF validiert. Er ist geeignet, in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Interleukin enhancer-binding factor 3 (ILF3) Antikörper (ABIN5696831)

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails

Verwendungszweck: ILF3 antibody

Immunogen: interleukin enhancer binding factor 3, 90kDa

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab04288( NF90,ILF3 Antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Antigendetails

Target: Interleukin enhancer-binding factor 3 (ILF3)

Andere Bezeichnung: ILF3

Hintergrund:

Synonyms: Interleukin enhancer-binding factor 3|Double-stranded RNA-binding protein 76 (DRBP76)|M-phase phosphoprotein 4 (MPP4)|Nuclear factor associated with dsRNA (NFAR)|Nuclear factor of activated T-cells 90 kDa (NF-AT-90)|Translational control protein 80 (TCP80)|ILF3|DRBF|MPHOSPH4|NF90

Background: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 90 kDa,110 kDa

Gen-ID: 3609

UniProt: Q12906

Pathways: M Phase