BIRC2 Antikörper (AA 320-570)

Produktnummer ABIN5693185

Produktdetails anti-BIRC2 Antikörper

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Bindungsspezifität: AA 320-570

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for cIAP1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human cIAP1 recombinant protein (Position: D320-T570).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu BIRC2

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Andere Bezeichnung: BIRC2 (BIRC2 Produkte)

Synonyme: API1 antikoerper, HIAP2 antikoerper, Hiap-2 antikoerper, MIHB antikoerper, RNF48 antikoerper, c-IAP1 antikoerper, cIAP1 antikoerper, Api2 antikoerper, rIAP1 antikoerper, IAP1 antikoerper, ITA antikoerper, AW146227 antikoerper, Api1 antikoerper, Birc3 antikoerper, HIAP1 antikoerper, IAP2 antikoerper, MIAP1 antikoerper, MIAP2 antikoerper, MIHC antikoerper, cIAP2 antikoerper, mcIAP1 antikoerper, ciap-1 antikoerper, birc3 antikoerper, api1 antikoerper, birc2 antikoerper, c-iap1 antikoerper, ciap1 antikoerper, hiap-2 antikoerper, hiap2 antikoerper, mihb antikoerper, rnf48 antikoerper, baculoviral IAP repeat containing 2 antikoerper, baculoviral IAP repeat-containing 2 antikoerper, baculoviral IAP repeat containing 2 L homeolog antikoerper, BIRC2 antikoerper, Birc2 antikoerper, birc2 antikoerper, birc2.L antikoerper

Hintergrund:

Synonyms: Baculoviral IAP repeat-containing protein 2

Tissue Specificity: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.

Background: Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene.The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q13490

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades