TPMT Antikörper (AA 1-245)

Produktnummer ABIN5693135

Produktdetails anti-TPMT Antikörper

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Bindungsspezifität: AA 1-245

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for TPMT detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human TPMT recombinant protein (Position: M1-K245).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu TPMT

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Andere Bezeichnung: TPMT (TPMT Produkte)

Synonyme: MGC84277 antikoerper, AW106912 antikoerper, NHLRC1 antikoerper, thiopurine S-methyltransferase L homeolog antikoerper, thiopurine S-methyltransferase, tandem duplicate 2 antikoerper, thiopurine S-methyltransferase TpmT antikoerper, thiopurine S-methyltransferase antikoerper, Thiopurine S-methyltransferase antikoerper, thiopurine methyltransferase antikoerper, tpmt.L antikoerper, tpmt.2 antikoerper, tpmT antikoerper, MCA0794 antikoerper, Pnap_4948 antikoerper, Hhal_1383 antikoerper, TK90_1044 antikoerper, Slit_1144 antikoerper, Tint_0842 antikoerper, Fbal_3334 antikoerper, Celly_3188 antikoerper, Weevi_1737 antikoerper, Psefu_2696 antikoerper, Metme_3860 antikoerper, Tpmt antikoerper, TPMT antikoerper

Hintergrund:

Synonyms: Thiopurine S-methyltransferase, Thiopurine methyltransferase, TPMT

Background: Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene. This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

UniProt: P51580