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TPMT Antikörper (AA 1-245)

TPMT Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3021279
  • Target Alle TPMT Antikörper anzeigen
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    Bindungsspezifität
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-245
    Reaktivität
    • 33
    • 12
    • 11
    • 2
    • 2
    Human
    Wirt
    • 28
    • 5
    Kaninchen
    Klonalität
    • 27
    • 6
    Polyklonal
    Konjugat
    • 19
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TPMT Antikörper ist unkonjugiert
    Applikation
    • 21
    • 15
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    MDGTRTSLDI EEYSDTEVQK NQVLTLEEWQ DKWVNGKTAF HQEQGHQLLK KHLDTFLKGK SGLRVFFPLC GKAVEMKWFA DRGHSVVGVE ISELGIQEFF TEQNLSYSEE PITEIPGTKV FKSSSGNISL YCCSIFDLPR TNIGKFDMIW DRGALVAINP GDRKCYADTM FSLLGKKFQY LLCVLSYDPT KHPGPPFYVP HAEIERLFGK ICNIRCLEKV DAFEERHKSW GIDCLFEKLY LLTEK
    Kreuzreaktivität
    Human
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human TPMT (NP_000358.1).
    Isotyp
    IgG
    Top Product
    Discover our top product TPMT Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:10 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TPMT (Thiopurine S-Methyltransferase (TPMT))
    Andere Bezeichnung
    TPMT (TPMT Produkte)
    Synonyme
    MGC84277 antikoerper, AW106912 antikoerper, NHLRC1 antikoerper, thiopurine S-methyltransferase L homeolog antikoerper, thiopurine S-methyltransferase, tandem duplicate 2 antikoerper, thiopurine S-methyltransferase TpmT antikoerper, thiopurine S-methyltransferase antikoerper, Thiopurine S-methyltransferase antikoerper, thiopurine methyltransferase antikoerper, tpmt.L antikoerper, tpmt.2 antikoerper, tpmT antikoerper, MCA0794 antikoerper, Pnap_4948 antikoerper, Hhal_1383 antikoerper, TK90_1044 antikoerper, Slit_1144 antikoerper, Tint_0842 antikoerper, Fbal_3334 antikoerper, Celly_3188 antikoerper, Weevi_1737 antikoerper, Psefu_2696 antikoerper, Metme_3860 antikoerper, Tpmt antikoerper, TPMT antikoerper
    Hintergrund
    This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.,TPMT,TPMTD,Signal Transduction,Endocrine & Metabolism,Drug metabolism,TPMT
    Molekulargewicht
    28 kDa
    Gen-ID
    7172
    UniProt
    P51580
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