TPMT Antikörper (AA 4-244)

Produktnummer ABIN7171992

Produktdetails anti-TPMT Antikörper

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Bindungsspezifität: AA 4-244

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Thiopurine S-methyltransferase protein (4-244AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TPMT

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Andere Bezeichnung: TPMT (TPMT Produkte)

Synonyme: MGC84277 antikoerper, AW106912 antikoerper, NHLRC1 antikoerper, thiopurine S-methyltransferase L homeolog antikoerper, thiopurine S-methyltransferase, tandem duplicate 2 antikoerper, thiopurine S-methyltransferase TpmT antikoerper, thiopurine S-methyltransferase antikoerper, Thiopurine S-methyltransferase antikoerper, thiopurine methyltransferase antikoerper, tpmt.L antikoerper, tpmt.2 antikoerper, tpmT antikoerper, MCA0794 antikoerper, Pnap_4948 antikoerper, Hhal_1383 antikoerper, TK90_1044 antikoerper, Slit_1144 antikoerper, Tint_0842 antikoerper, Fbal_3334 antikoerper, Celly_3188 antikoerper, Weevi_1737 antikoerper, Psefu_2696 antikoerper, Metme_3860 antikoerper, Tpmt antikoerper, TPMT antikoerper

Hintergrund:

Background: TPMT is an enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Aliases: HGNC:12014 antibody, S adenosyl L methionine thiopurine S methyltransferase antibody, Thiopurine methyltransferase antibody, Thiopurine S methyltransferase antibody, Thiopurine S-methyltransferase antibody, TPMT antibody, TPMT_HUMAN antibody

UniProt: P51580