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RAB27A Antikörper (AA 98-216)

RAB27A Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5692927
  • Target Alle RAB27A Antikörper anzeigen
    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
    Bindungsspezifität
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 98-216
    Reaktivität
    • 45
    • 21
    • 19
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 35
    • 7
    • 3
    • 2
    Kaninchen
    Klonalität
    • 37
    • 10
    Polyklonal
    Konjugat
    • 31
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAB27A Antikörper ist unkonjugiert
    Applikation
    • 32
    • 24
    • 10
    • 10
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    Anti-RAB27A Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-RAB27A Antibody Picoband® (ABIN5692927). Tested in ELISA, Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Immunogen
    E. coli-derived human RAB27A recombinant protein (Position: L98-K216).
    Isotyp
    IgG
    Top Product
    Discover our top product RAB27A Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
    Immunocytochemistry, 0.5-1 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells ELISA, 0.1-0.5 μg/mL
    1. Aksu, G., Kutukculer, N., Genel, F., Vergin, C., Omowaire, B. Griscelli syndrome without hemophagocytosis in an eleven-year-old girl: expanding the phenotypic spectrum ofRab27A mutations in humans. Am. J. Med. Genet. 116A: 329-333, 2003. 2. Kuroda, T. S., Fukuda, M., Ariga, H., Mikoshiba, K. The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J. Biol. Chem. 277: 9212-9218, 2002.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
    Andere Bezeichnung
    RAB27A (RAB27A Produkte)
    Hintergrund

    Synonyms: Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27

    Tissue Specificity: Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.

    Background: Ras-related protein Rab-27A is a protein that in humans is encoded by the RAB27A gene. The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

    Molekulargewicht
    27 kDa
    Gen-ID
    5873
    UniProt
    P51159
    Pathways
    Peptide Hormone Metabolism
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