RAB27A Antikörper (C-Term)

Produktnummer ABIN1440000

Produktdetails anti-RAB27A Antikörper

Target: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Schaf, Hund, Meerschweinchen, Kaninchen, Affe, Huhn, Schwein, Cat, Esel, Hamster, Avian

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser RAB27A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Detects Rab27a by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27a. This antibody also recognizes Rab27b protein.

Produktmerkmale: RAB27A, member RAS oncogene family

Aufreinigung: epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 120 aa to the C-terminus of mouse Rab27a produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Polyclonal antibody supplied as a 200 µL (1 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

Referenzen für anti-RAB27A Antikörper (ABIN1440000)

Alzahofi, Welz, Robinson, Page, Briggs, Stainthorp, Reekes, Elbe, Straub, Kallemeijn, Tate, Goff, Sviderskaya, Cantero, Montoliu, Nedelec, Miles, Bailly, Kerkhoff, Hume: "Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins." in: Nature communications, Vol. 11, Issue 1, pp. 3495, (2020) (PubMed).

Pelkonen, Reinisalo, Morin-Picardat, Kidron, Urtti: "Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160352, (2017) (PubMed).

Reichhart, Markowski, Ishiyama, Wagner, Crespo-Garcia, Schorb, Ramalho, Milenkovic, Föckler, Seabra, Strauß: "Rab27a GTPase modulates L-type Ca2+ channel function via interaction with the II-III linker of CaV1.3 subunit." in: Cellular signalling, Vol. 27, Issue 11, pp. 2231-40, (2016) (PubMed).

Details zu RAB27A

Target: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Andere Bezeichnung: Rab27a (RAB27A Produkte)

Synonyme: MGC80943 antikoerper, RAB27A antikoerper, gs2 antikoerper, ram antikoerper, rab27 antikoerper, MGC89827 antikoerper, hst18676 antikoerper, zgc:114135 antikoerper, GS2 antikoerper, HsT18676 antikoerper, RAB27 antikoerper, RAM antikoerper, 2210402C08Rik antikoerper, 2410003M20Rik antikoerper, 4933437C11Rik antikoerper, ash antikoerper, RAB27A, member RAS oncogene family L homeolog antikoerper, RAB27A, member RAS oncogene family antikoerper, RAB27A, member RAS oncogene family S homeolog antikoerper, rab27a.L antikoerper, RAB27A antikoerper, rab27a antikoerper, rab27a.S antikoerper, Rab27a antikoerper

Hintergrund: Rab27a belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and involved in lysosome-related vesicle transport and small GTPase mediated signal transduction.
Synonyms: GS2, GTP-binding protein Ram, rab-27, ras-related protein Rab-27A, RAB27, RAM.
Ensembl identifier: ENSG00000069974

Pathways: Peptide Hormone Metabolism