CD40 Ligand Antikörper (AA 107-260)
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- Target Alle CD40 Ligand (CD40LG) Antikörper anzeigen
- CD40 Ligand (CD40LG)
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Bindungsspezifität
- AA 107-260
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD40 Ligand Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Marke
- Picoband™
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
- Rabbit IgG polyclonal antibody for CD40L detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- Immunogen
- E. coli-derived mouse CD40L recombinant protein (Position: E107-L260).
- Top Product
- Discover our top product CD40LG Primärantikörper
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- Applikationshinweise
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- Target
- CD40 Ligand (CD40LG)
- Andere Bezeichnung
- Cd40lg (CD40LG Produkte)
- Synonyme
- CD154 antikoerper, cd40l antikoerper, CD40L antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TNFSF5 antikoerper, TRAP antikoerper, gp39 antikoerper, hCD40L antikoerper, CD40-L antikoerper, Cd40l antikoerper, Ly-62 antikoerper, Ly62 antikoerper, Tnfsf5 antikoerper, CD40 ligand antikoerper, TNF superfamily member 5 antikoerper, CD40LG antikoerper, cd40l antikoerper, Cd40lg antikoerper
- Hintergrund
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Synonyms: CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD154, CD40 ligand, membrane form, CD40 ligand, soluble form, Cd40lg, Cd40l, Tnfsf5
Tissue Specificity: Specifically expressed on activated CD4+ T- lymphocytes.
Background: CD40 ligand(CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb /IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells.CD40L plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the pathogenesis of coronary artery lesions.
- UniProt
- P27548
- Pathways
- NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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