TFEB Antikörper (AA 390-440)

Produktnummer ABIN5690285

Der Kaninchen Polyklonal anti-TFEB Antikörper (ABIN5690285) detektiert spezifisch TFEB in ELISA, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TFEB Antikörper (AA 390-440) (ABIN5690285)

Target: TFEB (Transcription Factor EB (TFEB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFEB Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TFEB Antikörper

Bindungsspezifität: AA 390-440

Spezifität: TFEB antibody is human specific. At least three isoforms of TFEB are known to exist.

Aufreinigung: TFEB antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal TFEB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TFEB.

The immunogen is located within amino acids 390 - 440 of TFEB.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TFEB antibody can be used for detection of TFEB by immunohistochemistry at 2.5 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TFEB antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TFEB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu TFEB

Target: TFEB (Transcription Factor EB (TFEB))

Andere Bezeichnung: TFEB

Hintergrund: The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors (1,2). Recent studies have shown that lysosomal biogenesis is regulated by TFEB (3), which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1 (4). Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes (5).

Gen-ID: 7942

NCBI Accession: NP_009093

UniProt: P19484