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FGFR3 Antikörper (AA 630-680)
FGFR3
Reaktivität: Human, Maus, Ratte
WB, ELISA, IHC (p), IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5689961
Produktdetails anti-FGFR3 Antikörper
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Target
Alle FGFR3 Antikörper anzeigen
FGFR3
(Fibroblast Growth Factor Receptor 3 (FGFR3))
Bindungsspezifität
Alle Epitope für FGFR3 Antikörper
AA 630-680
Reaktivität
Alle Reaktivitäten für FGFR3 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für FGFR3 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für FGFR3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für FGFR3 Antikörper
Dieser FGFR3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für FGFR3 Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Spezifität
FGFR3 antibody is human, mouse and rat reactive. At least three isoforms of FGFR3 are known to exist, this antibody will detect all three.
Aufreinigung
FGFR3 Antibody is affinity chromatography purified via peptide column.
Immunogen
FGFR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FGFR3. The immunogen is located within amino acids 630 - 680 of FGFR3.
Isotyp
IgG
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Discover our top product FGFR3 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
FGF3 antibody can be used for detection of FGFR3 by Western blot at 1 - 2 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
FGFR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
FGFR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu FGFR3
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Target
FGFR3
(Fibroblast Growth Factor Receptor 3 (FGFR3))
Andere Bezeichnung
FGFR3 (FGFR3 Produkte )
Synonyme
FGFR3 antikoerper, LOC100034114 antikoerper, ACH antikoerper, CD333 antikoerper, CEK2 antikoerper, HSFGFR3EX antikoerper, JTK4 antikoerper, FR3 antikoerper, Fgfr-3 antikoerper, Flg-2 antikoerper, HBGFR antikoerper, Mfr3 antikoerper, sam3 antikoerper, fc27h01 antikoerper, wu:fc27h01 antikoerper, fibroblast growth factor receptor 3 antikoerper, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antikoerper, FGFR3 antikoerper, fgfr3.S antikoerper, Fgfr3 antikoerper, fgfr3 antikoerper
Hintergrund
FGFR3 Antibody: FGFR3 is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis (1). It is required for normal skeleton development and promotes apoptosis in chondrocytes and cancer cell proliferation. FGFR3 protein contains three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain (1,2). It is alternatively spliced to produce three isoforms that are expressed in brain, kidney and testis. Defects in FGFR3 are associated with several diseases, including achondroplasia and hypochondroplasia (3,4). Mutations in FGFR3 are also a cause of some bladder and cervical cancers (5).
Molekulargewicht
Predicted: 89 kDa Observed: 9+2, 98 kDa
Gen-ID
2261
NCBI Accession
NP_001156685
UniProt
P22607
Pathways
RTK Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Stem Cell Maintenance , Growth Factor Binding
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