Fibrillarin Antikörper (AA 297-301)
Kurzübersicht für Fibrillarin Antikörper (AA 297-301) (ABIN5689460)
Target
Alle Fibrillarin (FBL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 297-301
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Spezifität
- This antibody detects endogenous level of total Fibrillarin protein.
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Aufreinigung
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- Fibrillarin antibody was raised against a peptide sequence around aa.297~301 ( L-T-L-E-P) derived from Human Fibrillarin.
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Applikationshinweise
- Western Blot: 1:500~1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store antibody at -20°C for up to one year.
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- Fibrillarin (FBL)
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Andere Bezeichnung
- Fibrillarin
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Hintergrund
- Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
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Molekulargewicht
- 37 kDa
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Gen-ID
- 2091
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NCBI Accession
- NP_001427
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UniProt
- P22087
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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