CDC25C Antikörper (AA 214-218)

Produktnummer ABIN5689442

Produktdetails anti-CDC25C Antikörper

Target: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Bindungsspezifität: AA 214-218

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC25C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Spezifität: This antibody detects endogenous level of total cdc25C protein.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: cdc25C (Ab-216) antibody was raised against a peptide sequence around aa.214~218 (S-P-S-M-P) derived from Human cdc25C.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu CDC25C

Target: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Andere Bezeichnung: cdc25C (CDC25C Produkte)

Synonyme: CDC25C antikoerper, cdc25 antikoerper, xcdc25c antikoerper, CDC25 antikoerper, PPP1R60 antikoerper, Cdc25 antikoerper, cdc25-3 antikoerper, xcdc25-3 antikoerper, cell division cycle 25C antikoerper, cell division cycle 25C S homeolog antikoerper, CDC25C antikoerper, cdc25c antikoerper, Cdc25c antikoerper, cdc25c.S antikoerper

Hintergrund: Cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Molekulargewicht: 60 kDa

Gen-ID: 995

NCBI Accession: NP_001781

UniProt: P30307

Pathways: Zellzyklus, M Phase