ASK1 Antikörper (AA 81-85)
Kurzübersicht für ASK1 Antikörper (AA 81-85) (ABIN5689421)
Target
Alle ASK1 (MAP3K5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 81-85
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Spezifität
- This antibody detects endogenous level of total ASK1 protein.
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Aufreinigung
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- ASK1 (Ab-83) antibody was raised against a peptide sequence around aa.81~85 (G-S-S-V-G) derived from Human ASK1.
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Applikationshinweise
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store antibody at -20°C for up to one year.
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- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
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Andere Bezeichnung
- ASK1
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Hintergrund
- Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
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Molekulargewicht
- 155 kDa
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Gen-ID
- 4217
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NCBI Accession
- NP_005914
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UniProt
- Q99683
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Pathways
- MAPK Signalweg, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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