MCL-1 Antikörper (AA 148-152)
Kurzübersicht für MCL-1 Antikörper (AA 148-152) (ABIN5689305)
Target
Alle MCL-1 (MCL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 148-152
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Spezifität
- This antibody detects endogenous level of total MCL1 protein.
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Aufreinigung
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- MCL1 antibody was raised against a peptide sequence around aa.148~152 (N-N-T-S-T) derived from Human MCL1.
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Applikationshinweise
- Western Blot: 1:500~1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store antibody at -20°C for up to one year.
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- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
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Andere Bezeichnung
- MCL1
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Hintergrund
- Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
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Molekulargewicht
- 42 kDa
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Gen-ID
- 4170
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NCBI Accession
- NP_068779
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UniProt
- Q07820
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Pathways
- MAPK Signalweg
Target
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