GRIA2 Antikörper (AA 878-882)

Produktnummer ABIN5689283

Dieses Anti-GRIA2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GRIA2 in WB. Geeignet für Human, Ratte und Maus.

Kurzübersicht für GRIA2 Antikörper (AA 878-882) (ABIN5689283)

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRIA2 Antikörper

Bindungsspezifität: AA 878-882

Spezifität: This antibody detects endogenous level of total Glutamate receptor 2 (Precursor) protein.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Glutamate receptor 2 (Precursor) (Ab-880) antibody was raised against a peptide sequence around aa.878~882 (I-E-S-V-K) derived from Human Glutamate receptor 2.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Andere Bezeichnung: Glutamate receptor 2

Hintergrund: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

Molekulargewicht: 100 kDa

Gen-ID: 2891

NCBI Accession: NP_000817

UniProt: P42262

Pathways: PI3K-Akt Signalweg