Der Huhn Polyklonal Anti-NEFL-Antikörper wurde für WB und IHC validiert. Er ist geeignet, NEFL in Proben von Human, Ratte, Maus, Rind (Kuh) und Huhn zu detektieren.
Specific for the ~68k Neurofilament L protein in Western blots and works well on frozen sections, cells in tissue culture and on mildly formalin fixed histological sections.
Aufreinigung
Total IgY fraction
Immunogen
Preparation of bovine spinal cord intermediate filaments
NEFL
Reaktivität: Schwein
WB, IF
Wirt: Maus
Monoclonal
DA2
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Lagerung
-20 °C
Informationen zur Lagerung
Neurofilament NF-L antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
Target
NEFL
(Neurofilament, Light Polypeptide (NEFL))
Andere Bezeichnung
Neurofilament NF-L
Hintergrund
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.