S100B Antikörper

Produktnummer ABIN5680133

Der Maus Monoklonal anti-S100B Antikörper (Klon SH-B1) (ABIN5680133) detektiert spezifisch S100B in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Rind (Kuh).

Kurzübersicht für S100B Antikörper (ABIN5680133)

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reaktivität: Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: SH-B1

Produktdetails anti-S100B Antikörper

Spezifität: S-100 beta, S-100 A (alpha/beta) and S-100 B (beta/beta), not reactive with S-100 A0 (alpha/alpha), Calmodulin, Parvalbumin and other Ca-binding proteins

Kreuzreaktivität (Details): Cattle, human, cat, rabbit, rat, pig

Produktmerkmale: The S-100 antibody has frequently been used for the detection of melanoic tumours. In brain tumours and metastases the antibody may be used for differentiation between glia derived tissue and tissues derived from other cell types. S-100 helps in differentiation of Melanoma and Schwannoma from other soft tissue tumours. It is also found in tumours of the salivary glands. S-100 is a homo- or heterodimer filament protein, composed of an alpha and a beta chain. In normal tissues it is found in glia and ependyma of the brain. In the periphery it is found in Schwann Cells, Melanocytes and in Langerhans Cells of the skin. In lymph nodes Interdigitating Cells are labelled. S-100 A0, which is exprimed e.g. by neurons, heart muscle and monocytes, will not be detected by this monoclonal antibody. S-100 ß, S-100 A (alpha/beta) and S-100 B (beta/beta), not reactive with S-100 A0 (alpha/alpha), Calmodulin, Parvalbumin and other Ca-binding proteins.

Aufreinigung: Antibody solution

Immunogen: Purified S-100beta protein from bovine brain

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Formaldehyde-fixed tissue should be pre-treated with 0.1 % pronase to give best results. Unmasking methods involving microwave or steam cooking are not recommended!,Skin, myelinated nerves,IHC(P),60 min at RT,(liquid conc.) Dilution 1:20 - 1:50 IHC(P)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: stabilizing phosphate buffer  pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 μL working solution / test)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Andere Bezeichnung: S-100 beta

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine