Cyclin E1 Antikörper
Kurzübersicht für Cyclin E1 Antikörper (ABIN567784)
Target
Alle Cyclin E1 (CCNE1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts with Cyclin E (50 kDa) on Imunoprecipitation.
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Aufreinigung
- Protein-A Agarose Chromatography of hybridoma supernatant.
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Immunogen
- Human recombinant full length His-Cyclin E.
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Isotyp
- IgG2b
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anti-Cyclin E1 (CCNE1) (AA 1-100) antibody
CCNE1 Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 1C8D4 unconjugated
anti-Cyclin E1 (CCNE1) (AA 307-410) antibodyCCNE1 Reaktivität: Human, Maus ELISA, FACS Wirt: Maus Monoclonal 5F8C5 unconjugated
anti-Cyclin E1 (CCNE1) (AA 10-176) antibodyCCNE1 Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal CCNE1-2460 unconjugated
anti-Cyclin E1 (CCNE1) (AA 375-411) antibodyCCNE1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-410) antibodyCCNE1 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (Thr395) antibodyCCNE1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) antibodyCCNE1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Monoclonal 3A5 unconjugated Recombinant Antibody
anti-Cyclin E1 (CCNE1) (AA 373-402), (C-Term) antibodyCCNE1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB07335 unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-410) antibodyCCNE1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (C-Term) antibodyCCNE1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Cyclin E1 (CCNE1)
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Andere Bezeichnung
- Cyclin E1
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Hintergrund
- Cyclin E, a positive regulator of the cell cycle, controls the transition of cells from G1 to S phase. Cyclin E forms a complex with Cdk2, the active kinase follows cyclin D/Cdk4 in progressively phosphorylating pRb, releasing it from members of the E2F family. E2F transcrIPPtion factors in turn activate a set of target genes that are essential for entry into S phase. Deregulation of the G1-S checkpoint contributes to uncontrolled cell division, a hallmark of cancer. Cyclin E overexpression and deregulation have been shown in several cancers including breast, colorectal, gastric and lung.Synonyms: CCNE, CCNE1, Cyclin-E1
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Gen-ID
- 898
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NCBI Accession
- NP_001229
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UniProt
- P24864
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Pathways
- Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
Target
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