TGFA Antikörper

Produktnummer ABIN5676024

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch TGFA in IHC, WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TGFA Antikörper (ABIN5676024)

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TGFA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Produktdetails anti-TGFA Antikörper

Kreuzreaktivität (Details): human TGFalpha 100%. (Neutralizing antibody)We found no crossreactivty to other cytokines such as hTGFß, hEGF, hPDGf, hTNF. hEPO, hIGF, 1mg per ml. hIL-1, hIL-2, hIL-3, hIL-4, hIL-5, hIL-6, hIL-7, hIL-8, hIL-9, hIL-10, hIL-11,and hIL-12

Aufreinigung: Purified

Endotoxin-Niveau: <0.1 EU per 1 µg of the antibody as determined by the LAL method.

Immunogen: TGF alpha antibody was raised in goat using E. coli-derived recombinant human TGF-alpha as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 2-8 µg/mL, IHC: 15 µg/mL, WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with PBS buffer.

Konzentration: Lot specific

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu TGFA

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Andere Bezeichnung: TGF alpha

Hintergrund: Transforming growth factor alpha (TGF- alpha) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGF alpha stimulates neural cell proliferation in the adult injured brain.

Pathways: NF-kappaB Signalweg, RTK Signalweg, EGFR Signaling Pathway