Rekombinanter CD38 Antikörper (AA 273-285)

Produktnummer ABIN5668195

Der Kaninchen Chimeric anti-CD38 Antikörper (Klon HB7) (ABIN5668195) detektiert spezifisch CD38 in FACS und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CD38 Antikörper (AA 273-285) (ABIN5668195)

Target: CD38

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD38 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: HB7

Produktdetails anti-CD38 Antikörper

Bindungsspezifität: AA 273-285

Verwendungszweck: Anti-CD38 [HB7], Rabbit IgG, kappa

Spezifität:

This antibody binds to an epitope between amino acids 273-285 of human CD38, an approximately 45 kDa type II transmembrane protein, expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. Also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Bimodally expressed during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. This antibody competes with clone AT13/5 (Ab00289) (Ellis 1995).

Application Notes original Clone: A customer reports successfully using this antibody (coupled to magnetic beads) for isolation of plasma cells from the intestinal lamina propria.

Produktmerkmale: This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Aufreinigung: Protein A affinity purified

Immunogen: Viable cells (1 x 10E7) of the human cell line, BJAB (Human Burkitt lymphoma B cell line), which was were injected intraperitoneally into 8-week-old BALB/c mice.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD38

Target: CD38

Hintergrund: ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase, EC 3.2.2.5, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38, p45, NAD(+) nucleosidase

UniProt: P28907