Telefon:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antikoerper-online.de

CD38 Antikörper Primary Antibody

Reaktivität: Human IHC, ELISA, WB Wirt: Maus Monoclonal 6E12D unconjugated
Pubmed (2)
Produktnummer ABIN969023
$410.30
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 3 bis 4 Werktagen
  • Target
    CD38
    Reaktivität
    Human
    • 176
    • 63
    • 20
    • 5
    • 2
    • 1
    • 1
    Wirt
    Maus
    • 120
    • 72
    • 35
    • 7
    • 1
    • 1
    Klonalität
    Monoklonal
    Konjugat
    Dieser CD38 Antikörper ist unkonjugiert
    • 75
    • 19
    • 17
    • 13
    • 12
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    • 168
    • 57
    • 55
    • 44
    • 35
    • 32
    • 29
    • 29
    • 26
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Aufreinigung
    Ascites
    Immunogen
    Purified recombinant fragment of human CD38 expressed in E. Coli.
    Klon
    6E12D
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Pavón, Muñoz, Navarro, Raya-Alvarez, Callejas-Rubio, Navarro-Pelayo, Ortego-Centeno, Sancho, Zubiaur: "Increased association of CD38 with lipid rafts in T cells from patients with systemic lupus erythematosus and in activated normal T cells." in: Molecular immunology, Vol. 43, Issue 7, pp. 1029-39, 2005 (PubMed).

    Liu, Verfaillie: "Myeloid-lymphoid initiating cells (ML-IC) are highly enriched in the rhodamine-c-kit(+)CD33(-)CD38(-) fraction of umbilical cord CD34(+) cells." in: Experimental hematology, Vol. 30, Issue 6, pp. 582-9, 2002 (PubMed).

  • Target
    CD38
    Abstract
    Antibody Abstract
    Synonyme
    T10, Cd38-rs1, cd38, ADPRC 1, cADPr hydrolase 1, CD38 molecule, CD38 antigen, CD38 molecule L homeolog, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CD38, Cd38, cd38.L
    Hintergrund
    CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.
    Molekulargewicht
    34 kDa
    Gen-ID
    952
    HGNC
    952
Sie sind hier:
help Kundenservice