CD42a Antikörper (PE)

Produktnummer ABIN5665750

Dieser Anti-CD42a-Antikörper ist ein Maus-Monoklonal-Antikörper zum Nachweis von CD42a in FACS. Geeignet für Human und Hund.

Kurzübersicht für CD42a Antikörper (PE) (ABIN5665750)

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Reaktivität: Human, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD42a Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: GR-P

Produktdetails anti-CD42a Antikörper (PE)

Verwendungszweck: Anti-Hu CD42a PE

Spezifität: The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.

Kreuzreaktivität (Details): Human, Canine (Dog)

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human acute lymphoblastic leukemia cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu CD42a

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Andere Bezeichnung: CD42a

Hintergrund: Glycoprotein IX platelet,CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.,GPIX, GP9

Gen-ID: 2815

UniProt: P14770