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CD42a Antikörper (PE)

Dieses Anti-CD42a-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD42a in FACS. Geeignet für Human und Hund.
Produktnummer ABIN5665750

Kurzübersicht für CD42a Antikörper (PE) (ABIN5665750)

Target

Alle CD42a (GP9) Antikörper anzeigen
CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Reaktivität

  • 67
  • 12
  • 9
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Hund

Wirt

  • 43
  • 30
Maus

Klonalität

  • 44
  • 28
  • 1
Monoklonal

Konjugat

  • 42
  • 9
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD42a Antikörper ist konjugiert mit PE

Applikation

  • 37
  • 28
  • 23
  • 19
  • 17
  • 16
  • 11
  • 2
  • 2
  • 1
Flow Cytometry (FACS)

Klon

GR-P
  • Verwendungszweck

    Anti-Hu CD42a PE

    Spezifität

    The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.

    Kreuzreaktivität (Details)

    Human, Canine (Dog)

    Aufreinigung

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    Human acute lymphoblastic leukemia cells

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target

    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

    Andere Bezeichnung

    CD42a

    Hintergrund

    Glycoprotein IX platelet,CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.,GPIX, GP9

    Gen-ID

    2815

    UniProt

    P14770
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