Dieses Maus Monoklonal-Antikörper erkennt spezifisch SMURF1 in WB, ELISA, IHC (p), IF und IP. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1x PBS, pH 7.4
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).
Murakami, Mathew, Huang, Farahani, Peng, Olson, Etlinger: "Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 7, pp. 805-13, (2010) (PubMed).
Target
SMURF1
(SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
Andere Bezeichnung
SMURF1
Hintergrund
Full Gene Name: SMAD specific E3 ubiquitin protein ligase 1 Synonyms: KIAA1625