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APC2 Antikörper (AA 51-90)

APC2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5647467
  • Target Alle APC2 Antikörper anzeigen
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    Bindungsspezifität
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-90
    Reaktivität
    • 28
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 27
    • 1
    Kaninchen
    Klonalität
    • 27
    • 1
    Polyklonal
    Konjugat
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APC2 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Antigen affinity purified
    Immunogen
    Amino acids 51-90 (KHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLK) from the human protein were used as the immunogen for the APC2 antibody.
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Western blot: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the APC2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    Andere Bezeichnung
    APC2 (APC2 Produkte)
    Synonyme
    APCL antikoerper, AI852447 antikoerper, R75424 antikoerper, APC2, WNT signaling pathway regulator antikoerper, adenomatosis polyposis coli 2 antikoerper, APC2 antikoerper, Apc2 antikoerper
    Hintergrund
    APC2, also called APCL or Adenomatous polyposis coli protein-like, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.
    UniProt
    O95996
    Pathways
    WNT Signalweg
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