RAPGEF2 Antikörper (AA 1398-1487)
RAPGEF2
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
1E8
unconjugated
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Target
Alle RAPGEF2 Antikörper anzeigen
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RAPGEF2
(Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
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Bindungsspezifität
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AA 1398-1487
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Reaktivität
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Human
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Wirt
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Maus
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Klonalität
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Monoklonal
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Konjugat
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Dieser RAPGEF2 Antikörper ist unkonjugiert
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Applikation
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Western Blotting (WB), ELISA
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Verwendungszweck
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Mouse monoclonal antibody raised against a partial recombinant RAPGEF2.
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Sequenz
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PITDFPEGHS HPARKPPDYN VALQRSRMVA RSSDTAGPSS VQQPHGHPTS SRPVNKPQWH KPNESDPRLA PYQSQGFSTE EDEDEQVSAV
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Kreuzreaktivität
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Human
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Produktmerkmale
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Antibody Reactive Against Recombinant Protein.
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Immunogen
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RAPGEF2 (XP_376350, 1398 a.a. ~ 1487 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Klon
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1E8
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Isotyp
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IgG1
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Applikationshinweise
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Optimal working dilution should be determined by the investigator.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Buffer
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In 1x PBS, pH 7.4
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Handhabung
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Aliquot to avoid repeated freezing and thawing.
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Lagerung
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-20 °C
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Informationen zur Lagerung
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Gloerich, ten Klooster, Vliem, Koorman, Zwartkruis, Clevers, Bos: "Rap2A links intestinal cell polarity to brush border formation." in: Nature cell biology, Vol. 14, Issue 8, pp. 793-801, (2012) (PubMed).
Pannekoek, van Dijk, Chan, Huveneers, Linnemann, Spanjaard, Brouwer, van der Meer, Zwartkruis, Rehmann, de Rooij, Bos: "Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control." in: Cellular signalling, Vol. 23, Issue 12, pp. 2056-64, (2011) (PubMed).
Letschka, Kollmann, Pfeifhofer-Obermair, Lutz-Nicoladoni, Obermair, Fresser, Leitges, Hermann-Kleiter, Kaminski, Baier: "PKC-theta selectively controls the adhesion-stimulating molecule Rap1." in: Blood, Vol. 112, Issue 12, pp. 4617-27, (2008) (PubMed).
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Target
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RAPGEF2
(Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
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Andere Bezeichnung
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RAPGEF2 (RAPGEF2 Produkte)
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Hintergrund
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Full Gene Name: Rap guanine nucleotide exchange factor (GEF) 2
Synonyms: CNrasGEF,NRAPGEP,PDZ-GEF1,PDZGEF1,RA-GEF,Rap-GEP
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Gen-ID
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9693
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NCBI Accession
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XM_376350
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Pathways
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Neurotrophin Signalübertragung
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