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RAPGEF2 Antikörper (AA 501-600)

RAPGEF2 Reaktivität: Human WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1387779
  • Target Alle RAPGEF2 Antikörper anzeigen
    RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
    Bindungsspezifität
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 501-600
    Reaktivität
    • 29
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 27
    • 2
    Kaninchen
    Klonalität
    • 28
    • 1
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAPGEF2 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 12
    • 12
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RAPGEF2
    Isotyp
    IgG
    Top Product
    Discover our top product RAPGEF2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
    Andere Bezeichnung
    RAPGEF2/PDZ-GEF1 (RAPGEF2 Produkte)
    Synonyme
    MGC83978 antikoerper, RAPGEF2 antikoerper, fa11h07 antikoerper, wu:fa11h07 antikoerper, CNrasGEF antikoerper, NRAPGEP antikoerper, PDZ-GEF1 antikoerper, PDZGEF1 antikoerper, RA-GEF antikoerper, Rap-GEP antikoerper, nRap GEP antikoerper, 5830453M24Rik antikoerper, CNRasGEF antikoerper, Pdzgef1 antikoerper, RA-GEF-1 antikoerper, mKIAA0313 antikoerper, nRapGEP antikoerper, Rap guanine nucleotide exchange factor 2 antikoerper, Rap guanine nucleotide exchange factor 2 L homeolog antikoerper, Rap guanine nucleotide exchange factor (GEF) 2 antikoerper, RAPGEF2 antikoerper, rapgef2.L antikoerper, rapgef2 antikoerper, Rapgef2 antikoerper
    Hintergrund

    Synonyms: KIAA0313, Neural RAP guanine nucleotide exchange protein, nRap GEP, NRAPGEP, PDZ domain containing guanine nucleotide exchange factor 1, PDZ domain-containing guanine nucleotide exchange factor 1, PDZ GEF1, PDZ-GEF1, PDZGEF1, RA GEF, RA-GEF, Rap guanine nucleotide exchange factor 2, Rapgef2, RPGF2_HUMAN.

    Background: PDZ-GEF1 is a 1,499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.

    Pathways
    Neurotrophin Signalübertragung
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