PVRL2 Antikörper (AA 58-212)
-
- Target Alle PVRL2 Antikörper anzeigen
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
-
Bindungsspezifität
- AA 58-212
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser PVRL2 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), ELISA
- Verwendungszweck
- CD112 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD112 (AA: 58-212) expressed in E. Coli.
- Klon
- 4A11B12
- Isotyp
- IgG1
- Top Product
- Discover our top product PVRL2 Primärantikörper
-
-
- Applikationshinweise
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- Target
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
- Andere Bezeichnung
- CD112 (PVRL2 Produkte)
- Hintergrund
-
Description: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Aliases: NECTIN2, HVEB, PRR2, PVRL2, PVRR2
- Molekulargewicht
- 57.7kDa
- Gen-ID
- 5819
- HGNC
- 5819
- UniProt
- Q92692
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
-