CD276 Antikörper (AA 29-466)

Produktnummer ABIN5611271

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD276 in ELISA, FACS, IHC und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD276 Antikörper (AA 29-466) (ABIN5611271)

Target: CD276

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD276 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: 8C1C2

Produktdetails anti-CD276 Antikörper

Bindungsspezifität: AA 29-466

Verwendungszweck: B7H3 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human B7H3 (AA: 29-466) expressed in HEK293 cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100 - 1/500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CD276

Target: CD276

Andere Bezeichnung: B7H3

Hintergrund: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 57.2 kDa

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints