PAX6 Antikörper

Produktnummer ABIN5596956

Produktdetails anti-PAX6 Antikörper

Target: PAX6 (Paired Box 6 (PAX6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Kreuzreaktivität (Details): Cross-reactivity with PAX6 from other sources has not been determined.

Produktmerkmale:

Sex: Female

Aufreinigung: Anti-PAX6 was purified from clarified ascites by Protein A chromatography.

Immunogen:

Immunogen: PAX6 protein A purified antibody was prepared in mice by repeated immunizations with a recombinant protein correspoding to human PAX6 protein.

Immunogen Type: Recombinant Protein

Klon: 7H10-D3-D4-G5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-PAX6 antibody is suitable for ELISA and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 46.7 kDa in size corresponding to PAX6 by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1:500 - 1:2,000

ELISA Dilution: 1:75,000 - 1:150,000

IF Microscopy Dilution: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Andere Bezeichnung: PAX6 (PAX6 Produkte)

Synonyme: pax6 antikoerper, an2 antikoerper, mgda antikoerper, wagr antikoerper, pax-6 antikoerper, pax6a antikoerper, xpax6 antikoerper, XLPAX6 antikoerper, MGC52531 antikoerper, PAX-6 antikoerper, AN antikoerper, AN2 antikoerper, D11S812E antikoerper, MGDA antikoerper, WAGR antikoerper, Pax-6 antikoerper, pax6b antikoerper, 1500038E17Rik antikoerper, AEY11 antikoerper, Dey antikoerper, Gsfaey11 antikoerper, Sey antikoerper, PAXZF-A antikoerper, Pax6.1 antikoerper, cb280 antikoerper, fc20e07 antikoerper, pax-a antikoerper, pax[zf-a] antikoerper, paxzfa antikoerper, wu:fc20e07 antikoerper, zfpax-6a antikoerper, zfpax-6b antikoerper, paired box 6 antikoerper, paired box 6 L homeolog antikoerper, paired box 6 S homeolog antikoerper, paired box 6a antikoerper, PAX6 antikoerper, pax6 antikoerper, Pax6 antikoerper, pax6.L antikoerper, pax6.S antikoerper, pax6a antikoerper

Hintergrund:

Synonyms: Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, AN2, PAX6 Antibody

Background: Paired box protein Pax-6 also known as aniridia type II protein (AN2) or oculorhombin is a transcription factor with key functions in the development of the eye, nose, central nervous system and pancreas. Pax6 further seems to be required for the differentiation of pancreatic islet alpha cells. PAX6 has been shown to bind to a promoter element in the glucagon, insulin and somatostatin promoters and regulates the specification of the ventral neuron subtypes by establishing the correct progenitor domains. Isoform 5a appears to function as a molecular switch that specifies target genes. Anti-PAX6 antibody is ideal for researchers interested in developmental biology, stem cell research, cell growth and cancer research.

Gene Name: PAX6

Gen-ID: 5080

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis