RPS6KA1 Antikörper (C-Term)
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- Target Alle RPS6KA1 Antikörper anzeigen
- RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RPS6KA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität (Details)
- A BLAST analysis was used to suggest cross reactivity with RSK1 proteins from human, rat and mouse. Partial reactivity may occur against RSK2 and RSK3 but has not been tested. Reactivity against homologues from other sources is not known.
- Aufreinigung
- This affinity-purified antibody is directed against the human RSK1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification.
- Immunogen
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-terminal region of human RSK1 protein.
Immunogen Type: Peptide
- Isotyp
- IgG
- Top Product
- Discover our top product RPS6KA1 Primärantikörper
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- Applikationshinweise
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Application Note: This affinity purified antibody has been tested for use in ELISA, western blot, and immunoprecipitation. Specific conditions for reactivity should be optimized by the end user. Expect a predominant band approximately 88 kDa in size corresponding to RSK1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:200 - 1:1000
ELISA Dilution: 1:2,000 - 1:5,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
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Buffer: 0.1 M Tris Chloride, 0.5 M Sodium Chloride, pH 8.0
Stabilizer: 50 % (v/v) Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Haltbarkeit
- 12 months
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- Target
- RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
- Andere Bezeichnung
- p90 RSK1 (RPS6KA1 Produkte)
- Synonyme
- HU-1 antikoerper, MAPKAPK1A antikoerper, RSK antikoerper, RSK1 antikoerper, Rsk1 antikoerper, p90rsk antikoerper, rsk antikoerper, RPS6KA antikoerper, hu-1 antikoerper, mapkapk1a antikoerper, rsk1 antikoerper, wu:fc56h07 antikoerper, zgc:152654 antikoerper, ribosomal protein S6 kinase A1 antikoerper, ribosomal protein S6 kinase polypeptide 1 antikoerper, ribosomal protein S6 kinase A1-like antikoerper, ribosomal protein S6 kinase A1 L homeolog antikoerper, ribosomal protein S6 kinase a, polypeptide 1 antikoerper, RPS6KA1 antikoerper, Rps6ka1 antikoerper, RPS6KA1L antikoerper, rps6ka1.L antikoerper, rps6ka1 antikoerper
- Hintergrund
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Synonyms: 90 kDa ribosomal protein S6 kinase 1 antibody, dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1 antibody, dJ590P13.1 antibody, EC 2.7.11.1 antibody, HU 1 antibody
Background: RSK1 is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsk's appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK1 is studied in cancer research and is known to inactive tumor supressor complexes and death kinases.
Gene Name: RPS6KA1, RSK1
- Gen-ID
- 6195
- UniProt
- Q15418
- Pathways
- MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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