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Retinoblastoma 1 Antikörper (pSer807)

RB1 Reaktivität: Human, Maus, Ratte WB, IF (cc) Wirt: Kaninchen Monoclonal 2D10 unconjugated
Produktnummer ABIN5557520
  • Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen
    Retinoblastoma 1 (RB1)
    Bindungsspezifität
    • 35
    • 27
    • 25
    • 24
    • 23
    • 21
    • 19
    • 15
    • 11
    • 10
    • 10
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer807
    Reaktivität
    • 273
    • 114
    • 99
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 239
    • 36
    Kaninchen
    Klonalität
    • 235
    • 40
    Monoklonal
    Konjugat
    • 126
    • 19
    • 17
    • 16
    • 11
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
    Applikation
    • 204
    • 121
    • 110
    • 79
    • 79
    • 38
    • 31
    • 28
    • 27
    • 20
    • 15
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Synthetic peptide derived from human Rb(S807), around 800-850aa (phospho S807).
    Klon
    2D10
    Isotyp
    IgG
    Top Product
    Discover our top product RB1 Primärantikörper
  • Applikationshinweise
    WB 1:1000-2000
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C
    Haltbarkeit
    12 months
  • Target
    Retinoblastoma 1 (RB1)
    Andere Bezeichnung
    Rb (RB1 Produkte)
    Synonyme
    OSRC antikoerper, RB antikoerper, p105-Rb antikoerper, pRb antikoerper, pp110 antikoerper, Rb antikoerper, Rb-1 antikoerper, P105-RB antikoerper, PP110 antikoerper, RB11 antikoerper, zgc:154147 antikoerper, RB transcriptional corepressor 1 antikoerper, RB transcriptional corepressor like 1 antikoerper, retinoblastoma 1 antikoerper, RB1 antikoerper, RBL1 antikoerper, Rb1 antikoerper, rb1 antikoerper
    Hintergrund

    Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

    Synonyms: RbSer780, OSRC, P105 RB, P105RB, PP105, PP110, pRb, RB 1, RB1, RB1 protein, Retinoblastoma 1 including osteosarcoma, Retinoblastoma 1, Retinoblastoma associated protein, Including osteosarcoma, Osteosarcoma, p105-Rb, Rb, RB_HUMAN, Retinoblastoma suspectibility protein, Retinoblastoma-associated protein, Retinoblastoma related osteosarcoma, Retinoblastoma susceptibility gene.

    Gen-ID
    5925
    UniProt
    P06400
    Pathways
    Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
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