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Nanog Antikörper

NANOG Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Monoclonal 1A11 unconjugated
Produktnummer ABIN5557500
  • Target Alle Nanog (NANOG) Antikörper anzeigen
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Reaktivität
    • 131
    • 59
    • 22
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 120
    • 17
    • 3
    • 1
    Kaninchen
    Klonalität
    • 116
    • 25
    Monoklonal
    Konjugat
    • 76
    • 9
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Nanog Antikörper ist unkonjugiert
    Applikation
    • 109
    • 59
    • 43
    • 43
    • 26
    • 26
    • 19
    • 18
    • 18
    • 15
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant human Nanog protein, around N-terminal 1-100aa.
    Klon
    1A11
    Isotyp
    IgG
    Top Product
    Discover our top product NANOG Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Andere Bezeichnung
    Nanog (NANOG Produkte)
    Synonyme
    2410002E02Rik antikoerper, ENK antikoerper, ecat4 antikoerper, NANOG antikoerper, hacp antikoerper, wu:fd19e04 antikoerper, wu:fd20a07 antikoerper, zgc:193933 antikoerper, Nanog homeobox antikoerper, nanog homeobox antikoerper, Nanog antikoerper, NANOG antikoerper, nanog antikoerper
    Hintergrund

    Synonyms: Homeobox protein NANOG, NANOG

    Background: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.

    Gen-ID
    79923
    UniProt
    Q9H9S0
    Pathways
    Stem Cell Maintenance
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