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Nanog Antikörper (N-Term)

NANOG Reaktivität: Human, Maus WB, IF, ICC, ChIP-seq, ChIP, CUT&RUN Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6972403
  • Target Alle Nanog (NANOG) Antikörper anzeigen
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Bindungsspezifität
    • 16
    • 16
    • 12
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 139
    • 59
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 127
    • 18
    • 3
    • 1
    Kaninchen
    Klonalität
    • 122
    • 27
    Polyklonal
    Konjugat
    • 79
    • 10
    • 9
    • 9
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Nanog Antikörper ist unkonjugiert
    Applikation
    • 117
    • 65
    • 48
    • 46
    • 26
    • 26
    • 24
    • 18
    • 17
    • 17
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP), Cleavage Under Targets and Release Using Nuclease (CUT&RUN)
    Produktmerkmale
    Nanog (Nanog homeobox) is a transcriptional regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity). Nanog antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
    Aufreinigung
    Affinity Purified
    Immunogen
    This antibody was raised against a peptide within the N-terminal region of mouse Nanog.
    Isotyp
    IgG
    Top Product
    Discover our top product NANOG Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Andere Bezeichnung
    Nanog (NANOG Produkte)
    Synonyme
    2410002E02Rik antikoerper, ENK antikoerper, ecat4 antikoerper, NANOG antikoerper, hacp antikoerper, wu:fd19e04 antikoerper, wu:fd20a07 antikoerper, zgc:193933 antikoerper, Nanog homeobox antikoerper, nanog homeobox antikoerper, Nanog antikoerper, NANOG antikoerper, nanog antikoerper
    Molekulargewicht
    45 kDa
    NCBI Accession
    NP_082292
    Pathways
    Stem Cell Maintenance
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