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P2RX7 Antikörper (AA 226-452)

P2RX7 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 7G1D6 unconjugated
Produktnummer ABIN5542663
  • Target Alle P2RX7 Antikörper anzeigen
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 226-452
    Reaktivität
    • 46
    • 38
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 53
    • 4
    • 2
    • 1
    Maus
    Klonalität
    • 54
    • 6
    Monoklonal
    Konjugat
    • 31
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser P2RX7 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 24
    • 18
    • 13
    • 13
    • 10
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    P2RX7 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human P2RX7 (AA: 226-452) expressed in E. Coli.
    Klon
    7G1D6
    Isotyp
    IgG2b
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Andere Bezeichnung
    P2RX7 (P2RX7 Produkte)
    Hintergrund

    Description: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

    Aliases: P2X7

    Molekulargewicht
    68.6kDa
    Gen-ID
    5027
    HGNC
    EF011664.1
    UniProt
    Q99572
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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