CSF1R Antikörper (AA 20-152)
Kurzübersicht für CSF1R Antikörper (AA 20-152) (ABIN5542590)
Target
Alle CSF1R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 20-152
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Verwendungszweck
- CSF1R Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CSF1R (AA: 20-152) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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Andere Bezeichnung
- CSF1R
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Hintergrund
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The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
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Molekulargewicht
- 108 kDa
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Gen-ID
- 1436
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UniProt
- P07333
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Pathways
- RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization
Target
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