IRAK3 Antikörper (AA 454-596)
Kurzübersicht für IRAK3 Antikörper (AA 454-596) (ABIN5542522)
Target
Alle IRAK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 454-596
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Verwendungszweck
- IRAK3 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human IRAK3 (AA: 454-596) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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Andere Bezeichnung
- IRAK3
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Hintergrund
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This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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Molekulargewicht
- 67.8 kDa
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Gen-ID
- 11213
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UniProt
- Q9Y616
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Target
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