MECP2 Antikörper (AA 7-148)
Kurzübersicht für MECP2 Antikörper (AA 7-148) (ABIN5542475)
Target
Alle MECP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 7-148
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Verwendungszweck
- MECP2 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human MECP2 (AA: 7-148) expressed in E. Coli.
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Isotyp
- IgG1
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anti-Methyl CpG Binding Protein 2 (MECP2) (pSer423) antibody
MECP2 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB29261 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibodyMECP2 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1B11 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 400-428) antibodyMECP2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB25959 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-100) antibodyMECP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) antibodyMECP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 58-87), (N-Term) antibodyMECP2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB27934 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (C-Term) antibodyMECP2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-30), (N-Term) antibodyMECP2 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB2387 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (pSer80) antibodyMECP2 Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB27934 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 399-428), (C-Term) antibodyMECP2 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB2386 unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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Andere Bezeichnung
- MECP2
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Hintergrund
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DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
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Molekulargewicht
- 52.4 kDa
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UniProt
- P51608
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Pathways
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
Target
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