ESRRA Antikörper (AA 198-376)

Produktnummer ABIN5542454

Dieser Maus Monoklonal Antikörper erkennt spezifisch ESRRA in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ESRRA Antikörper (AA 198-376) (ABIN5542454)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 1A6E11

Produktdetails anti-ESRRA Antikörper

Bindungsspezifität: AA 198-376

Verwendungszweck: ESRRA Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human ESRRA (AA: 198-376) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: ESRRA

Hintergrund: The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 45.5 kDa

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha