LDLR Antikörper (AA 22-150)

Produktnummer ABIN5542334

Dieses Maus Monoklonal-Antikörper erkennt spezifisch LDLR in IHC, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LDLR Antikörper (AA 22-150) (ABIN5542334)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LDLR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon: 1B10H10

Produktdetails anti-LDLR Antikörper

Bindungsspezifität: AA 22-150

Verwendungszweck: LDLR Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human LDLR (AA: 22-150) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Andere Bezeichnung: LDLR

Hintergrund: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.r

Molekulargewicht: 95.4 kDa

Gen-ID: 3949

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism