LDLR Antikörper (AA 391-419)

Produktnummer ABIN652907

Der Kaninchen Polyklonal anti-LDLR Antikörper wird verwendet zum Nachweis von LDLR in Proben von Human und Maus. Er wurde validiert für WB und FACS.

Kurzübersicht für LDLR Antikörper (AA 391-419) (ABIN652907)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDLR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB22886

Produktdetails anti-LDLR Antikörper

Bindungsspezifität: AA 391-419

Homologie: X, B, Ha, Pig, Rb, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids of human LDLR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Andere Bezeichnung: LDLR

Hintergrund: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.

Molekulargewicht: 95376

Gen-ID: 3949

NCBI Accession: NP_000518, NP_001182727, NP_001182728, NP_001182729, NP_001182732

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism