CD46 Antikörper (AA 35-313)

Produktnummer ABIN5541991

Dieses Anti-CD46-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD46 in WB und EIA. Geeignet für Human.

Kurzübersicht für CD46 Antikörper (AA 35-313) (ABIN5541991)

Target: CD46

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT2G9

Produktdetails anti-CD46 Antikörper

Bindungsspezifität: AA 35-313

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human CD46 (35-313aa) purified from E. coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD46

Target: CD46

Andere Bezeichnung: cd46,mcp

Hintergrund: Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types.

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization