CD46 Antikörper

Produktnummer ABIN5541989

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CD46 in WB, FACS, IF, ICC und EIA. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für CD46 Antikörper (ABIN5541989)

Target: CD46

Reaktivität: Maus, Ratte

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

Klon: MM10

Produktdetails anti-CD46 Antikörper

Spezifität: The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46.

Aufreinigung: Purified

Immunogen: Mouse CD46-human Fc fusion protein.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immuno Assays (Detector) Positive Control: Rat CD46 or Mouse CD46 variant as coating on a micro titer plate. Western blot (Researcher data). Flow Cytometry (Researcher data) Immunefluorescence Immuno histochemistry on Frozen Sections The typical starting working dilution is 1/50.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.02 % Sodium Azide Stabilizers: 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD46

Target: CD46

Andere Bezeichnung: cd46,mcp

Hintergrund: MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria.

UniProt: O88174

Pathways: Regulation of Actin Filament Polymerization