CD46 Antikörper

Produktnummer ABIN5541989

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CD46 in WB, FACS, IF, ICC und EIA. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für CD46 Antikörper (ABIN5541989)

Target: CD46

Reaktivität: Maus, Ratte

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

Klon: MM10

Produktdetails anti-CD46 Antikörper

Spezifität: The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46.

Aufreinigung: Purified

Immunogen: Mouse CD46-human Fc fusion protein.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immuno Assays (Detector) Positive Control: Rat CD46 or Mouse CD46 variant as coating on a micro titer plate. Western blot (Researcher data). Flow Cytometry (Researcher data) Immunefluorescence Immuno histochemistry on Frozen Sections The typical starting working dilution is 1/50.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.02 % Sodium Azide Stabilizers: 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD46

Target: CD46

Andere Bezeichnung: cd46,mcp

Hintergrund: MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria.

UniProt: O88174

Pathways: Regulation of Actin Filament Polymerization