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LRRC32 Antikörper

LRRC32 Reaktivität: Human WB, FACS, IP, EIA Wirt: Maus Monoclonal GARP5 unconjugated
Produktnummer ABIN5541855
  • Target Alle LRRC32 Antikörper anzeigen
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Reaktivität
    • 26
    • 11
    • 9
    • 1
    Human
    Wirt
    • 21
    • 12
    • 4
    • 1
    Maus
    Klonalität
    • 22
    • 16
    Monoklonal
    Konjugat
    • 20
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Dieser LRRC32 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 15
    • 15
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
    Aufreinigung
    Protein-A affinity chromatography
    Immunogen
    Purified human sGARP protein
    Klon
    GARP5
    Isotyp
    IgG1
    Top Product
    Discover our top product LRRC32 Primärantikörper
  • Applikationshinweise
    Flow cytometry. Immunoprecipitation. Western blot. ELISA.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Andere Bezeichnung
    lrrc32,garp (LRRC32 Produkte)
    Hintergrund
    GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
    UniProt
    Q14392
    Pathways
    Activated T Cell Proliferation
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