LRRC32 Antikörper

Produktnummer ABIN5541855

Der Maus Monoklonal anti-LRRC32 Antikörper wird verwendet zum Nachweis von LRRC32 in Proben von Human. Er wurde validiert für WB, FACS, IP und EIA.

Kurzübersicht für LRRC32 Antikörper (ABIN5541855)

Target: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LRRC32 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Klon: GARP5

Produktdetails anti-LRRC32 Antikörper

Spezifität: This antibody recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.

Aufreinigung: Protein-A affinity chromatography

Immunogen: Purified human sGARP protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry. Immunoprecipitation. Western blot. ELISA.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu LRRC32

Target: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Andere Bezeichnung: lrrc32,garp

Hintergrund: GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.

UniProt: Q14392

Pathways: Activated T Cell Proliferation